Johnson & Johnson to Present New Scientific Data on ACUVUE OASYS MAX 1-Day, TECNIS Odyssey, and a Purely Refractive Next Generation EDF IOL^{^} at ARVO 2025

JACKSONVILLE, FL – May 4, 2025 - Johnson & Johnson^† will present new data on several of its latest innovations through 35+ posters and oral presentations at the 2025 Association for Research in Vision and Ophthalmology (ARVO) annual meeting on May 4 - 8. The eye health innovations from Johnson & Johnson are backed by robust clinical studies and data sets.

• New in-vitro methodology shows that ACUVUE OASYS MAX 1-Day (vs. competitor) maintained lubricity at end of day in dehydrating conditions. 

• New study highlights TECNIS Odyssey IOL as utilizing light efficiently supporting image quality and visual acuity 

• New research on a purely refractive next generation of EDF IOL^{^} in new vision test shows that it has better tolerance to refractive errors compared to a multifocal IOL. 

• Additional new data to be presented on astigmatism, presbyopia, myopia management and refractive technology 

“Our innovations in ACUVUE contact lenses, TECNIS IOLs, cataract and refractive technologies are addressing high unmet needs and are always rooted in scientific data,” said Xiao-Yu Song, Global Head of R&D, Vision, Johnson & Johnson. ^* “We are excited to share this latest research that demonstrates our leadership in optical and material science, in order to help improve patient outcomes.”

New in-vitro methodology shows that ACUVUE OASYS MAX 1-Day (vs. competitor) maintained lubricity at end of day in dehydrating conditions

A new stress test, compared contact lens material surface behavior under challenging conditions such as evaporative stress and dehydration (which may cause discomfort and compromise ocular surface health), and measured lower friction for ACUVUE^® OASYS MAX 1-Day than Dailies Total1^®.

• An evaporative stress tribological assay for insights into contact lens materials behavior under challenging conditions. Tosatti, Samuele et al. (Oral Presentation: May 8, 3:15 – 3:30PM MT)
• The characterization of silicone hydrogel materials using a Tribological Stress Test (TST). Mohammed, Chrysan. (Poster Presentation: May 7, 2:00 – 3:45PM MT)

New clinical data shows benefits of astigmatism correction for multifocal content lens wearers

This clinical study of 384 presbyopic patients wearing ACUVUE^® OASYS MAX 1-Day Multifocal contact lens suggest that the benefit of correcting 0.75 diopter of astigmatism for wearers of multifocal contact lenses is less impactful than for those who wear spherical (non-multifocal) contact lenses.

• Visual performance of multifocal contact lens wearers with 0.75D of uncorrected astigmatism. Ross, Franklin et al. (Poster presentation: May 4, 8:00 – 9:45AM MT)

TECNIS Odyssey IOL shown to utilize light efficiently which impacts image quality and visual acuity in new study

This study evaluates methods for assessing light distribution of diffractive intraocular lenses. It evaluates which fraction of the incoming light energy truly contributes to the retinal image quality and its subsequent contribution to visual acuity. The research highlights modulation transfer function (MTF) area under the curve, compared with conventional methods for assessing light distribution, as a good metric for evaluating diffractive PC IOLs, such as the TECNIS Odyssey IOL.

• Light utilization of diffractive intraocular lenses. Henk, Weber. (Poster Presentation: May 8, 8:00 – 9:45AM MT)

Research on extended depth of focus PC-IOLs, including a purely refractive next generation of EDF IOL^{^}

Several studies on a purely refractive next generation of EDF IOL^{^}, including a new vision performance test to assess functional vision which can complement conventional threshold vision tests; image quality differences between EDF models; and research on post-operative refractive errors.

• Quick Vision Performance Test - A new method for analysing performance of Intraocular lenses. Romashchenko, Dmitry et al. (Poster presentation: May 4, 1:00 – 2:45PM MT)
• Optical bench evaluation of decentration effect on extended depth of focus (EDF) intraocular lenses. Alarcon, Aixa et al. (Poster presentation: May 5, 3:00 – 4:45PM MT)
• Difference between uncorrected distance visual acuity and defocus curve testing with trial lenses of myopic and hyperopic pseudophakic eyes. Papadatou, Eleni et al. (Poster presentation: May 4, 8:00 – 9:45AM MT)
• Effects of post-operative refractive errors in presbyopia correcting intraocular lenses in post-LASIK eyes. Jenkins, Mark et al. (Poster presentation: May 8, 8:00 – 9:45AM MT)

Real world evidence and research on myopia management including solutions like a soft contact lens with the RingBoost Technology^TM

Data includes a 12-month real-world study report of safety and performance of a soft contact lens with the RingBoost Technology^TM worn by Chinese children in Hainan, China. Additional research examines how to properly evaluate effectiveness of myopia control treatment considering limitations of using the centile growth and large variance in underlying eye growth in treated eyes.

• Real-world safety and performance of a novel soft contact lens for myopia management in Chinese children. Cheng, Xu et al. (Poster presentation: May 7, 2:00 – 3:45PM MT)
• The Limitations of Percentile Growth Curves for Myopia. Bullimore, Mark et al. (Poster presentation: May 7, 2:00 – 3:45PM MT)
• What percentage of individuals treated for myopia progression exhibit axial elongation greater than the mean of the control group? Brennan, Noel et al. (Poster presentation: May 7, 2:00 – 3:45PM MT)

Additionally, Johnson & Johnson will be sharing 5 company-sponsored presentations highlighting research in geographic atrophy, including real-world evidence, imaging biomarker analyses and physician preference data.

Additional poster and oral presentations from Johnson & Johnson at the ARVO 2025 Annual Meeting can be found through the event Online Meeting Planner.

^* Xiao-Yu Song, MD, Ph.D. is an employee of Johnson & Johnson Vision Care, Inc.

^{^} The purely refractive next generation EDF IOL has not received pre-market approval in the U.S.

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^†About Vision at Johnson & Johnson

Johnson & Johnson has a deep legacy in developing transformational new products that improve the health of patients’ eyes. We have a bold ambition: Vision Made Possible – improving sight for more than 40 million people each year. Through cutting-edge innovation, expertise in material and optical science, and advanced technologies, we are revolutionizing the way people see and experience the world. Visit us at clearvisionforyou.com, follow @JNJVision on Twitter, Johnson & Johnson | Vision on LinkedIn, and @JNJVision on Facebook.

Media Contact

Janet Cheng

Vision, Johnson & Johnson

[email protected]

Important information for Contact Lens Wearers: ACUVUE Contact Lenses are available by prescription only for vision correction. An eye care professional will determine whether contact lenses are right for you. Although rare, serious eye problems can develop while wearing contact lenses. To help avoid these problems, follow the wear and replacement schedule and the lens care instructions provided by your eye doctor. Do not wear contact lenses if you have an eye infection, or experience eye discomfort, excessive tearing, vision changes, redness or other eye problems. If one of these conditions occurs, remove the lens and contact your eye doctor immediately. For more information on proper wear, care and safety, talk to your eye care professional, call 1-800-843-2020, or download the Patient Instruction Guides.

INDICATIONS AND IMPORTANT SAFETY INFORMATION FOR TECNIS ODYSSEY^™ IOL WITH TECNIS SIMPLICITY^™ DELIVERY SYSTEM, MODEL DRN00V AND TECNIS ODYSSEY^™ TORIC II IOL WITH TECNIS SIMPLICITY^™ DELIVERY SYSTEM, MODELS DRT150, DRT225, DRT300, DRT375

Rx Only

INDICATIONS:

The TECNIS SIMPLICITY^™ Delivery System is used to fold and assist in inserting the TECNIS Odyssey^™ IOL, which is indicated for primary implantation for the visual correction of aphakia in adult patients, with less than 1 diopter of pre-existing corneal astigmatism, in whom a cataractous lens has been removed. The TECNIS SIMPLICITY^™ Delivery System is used to fold and assist in inserting the TECNIS Odyssey^™ Toric II IOLs that are indicated for primary implantation for the visual correction of aphakia and for reduction of refractive astigmatism in adult patients with greater than or equal to 1 diopter of preoperative corneal astigmatism, in whom a cataractous lens has been removed. Compared to an aspheric monofocal lens, the TECNIS Odyssey^™ IOLs mitigate the effects of presbyopia by providing improved visual acuity at intermediate and near distances to reduce eyeglass wear, while maintaining comparable distance visual acuity. The lens is intended for capsular bag placement only.

WARNINGS

Intraocular lenses may exacerbate an existing condition, may interfere with diagnosis or treatment of a condition or may pose an unreasonable risk to the eyesight of patients. Patients should have well-defined visual needs and be informed of possible visual effects (such as a perception of halo, starburst or glare around lights), which may be expected in nighttime or poor visibility conditions. Patients may perceive these visual effects as bothersome, which, on rare occasions, may be significant enough for the patient to request removal of the IOL. The physician should carefully weigh the potential risks and benefits for each patient. Patients with a predicted postoperative residual astigmatism greater than 1.0 diopter, with or without a toric lens, may not fully benefit in terms of reducing spectacle wear. Rotation of the TECNIS Odyssey^™ Toric II IOL from its intended axis can reduce its astigmatic correction. Misalignment greater than 30° may increase postoperative refractive cylinder. If necessary, lens repositioning should occur as early as possible, prior to lens encapsulation. The lens and delivery system should be discarded if the lens has been folded within the cartridge for more than 10 minutes. Not doing so may result in the lens being stuck in the cartridge. Do not attempt to disassemble, modify, or alter the delivery system or any of its components, as this can significantly affect the function and/or structural integrity of the design.

PRECAUTIONS

Interpret results with caution when using autorefractors or wavefront aberrometers that utilize infrared light, or when performing a duochrome test. Confirmation of refraction with maximum plus manifest refraction technique is strongly recommended. The ability to perform some eye treatments (e.g., retinal photocoagulation) may be affected by the IOL optical design. The surgeon should target emmetropia, as this lens is designed for optimum visual performance when emmetropia is achieved. The TECNIS Odyssey^™ IOLs should not be placed in the ciliary sulcus. Carefully remove all viscoelastic and do not over-inflate the capsular bag at the end of the case. Residual viscoelastic and/or over-inflation of the capsular bag may allow the lens to rotate, causing misalignment of the TECNIS Odyssey^™ Toric II IOL. All preoperative surgical parameters are important when choosing a TECNIS Odyssey^™ Toric II IOL for implantation, including preoperative keratometric cylinder (magnitude and

axis), incision location, the surgeon's estimated surgically induced astigmatism (SIA) and biometry. Variability in any of the preoperative measurements can influence patient outcomes and the effectiveness of treating eyes with lower amounts of preoperative corneal astigmatism. The effectiveness of TECNIS Odyssey^™ Toric II IOLs in reducing postoperative residual astigmatism in patients with preoperative corneal astigmatism < 1.0 diopter has not been demonstrated. Patients with a predicted postoperative astigmatism greater than 1.0 D may not be suitable candidates for implantation with the TECNIS Odyssey^™ IOLs, as they may not obtain the benefits of reduced spectacle wear or improved intermediate and near vision seen in patients with lower predicted postoperative astigmatism.